The use of biodegradable temporising matrix for reconstructive salvage following full-thickness chest wall skin graft failure – A case report
Gregory, Harrison Haeata Keane, Auld, Michael Craig, and Ferris, Baillie Ward Churchill (2025) The use of biodegradable temporising matrix for reconstructive salvage following full-thickness chest wall skin graft failure – A case report. Jpras Open, 46. pp. 211-215.
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Abstract
NovoSorb biodegradable temporising matrix (BTM) has emerged as an effective material in the resurfacing of pathologies requiring extensive debridement or tissue loss, such as burns, necrotising soft tissue infections, and tumour excision. The use of BTM in cases of reconstructive salvage following graft failure is less well documented in the literature. We report a case of a 70-year-old female who initially underwent a wide local excision of a large chest wall basal cell carcinoma and full-thickness skin grafting of the resulting defect. Following graft failure and re-debridement, BTM application and consequent split-thickness grafting resulted in a successful reconstructive salvage and cosmetic outcome. This case reinforces the wide-ranging application of BTM in the reconstructive setting, and highlights the effectiveness of BTM in cases of graft failure requiring reconstructive salvage.
| Item ID: | 89873 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 2352-5878 |
| Keywords: | Basal cell carcinoma, Biodegradable temporising matrix, Full-thickness skin graft |
| Copyright Information: | © 2025 The Author(s). Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Date Deposited: | 22 Jul 2026 01:19 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3206 Medical biotechnology > 320606 Regenerative medicine (incl. stem cells) @ 50% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320226 Surgery @ 50% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100% |
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