Kidanemarium, A., Gouws, J., van Vuuren, M., and Gummow, B. (2005) In vitro antimicrobial susceptibility of Mycoplasma mycoides mycoides large colony and Arcaobacterium pyogenes isolated from clinical cases of ulcerative balanitis and vulvitis in Dorper sheep in South Africa. Journal of the South African Veterinary Association, 76 (4). pp. 204-208.

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Abstract

The in vitro activities of enrofloxacin, florfenicol, oxytetracycline and spiramycin were determined against field isolates of A1ycoplasma mycoides mycoides large colony (Mmm LC) by means of the broth microdilution technique. The minimum inhibitory concentrations (MICs) of these antimicrobial drugs were determined for a representative number of 10 isolates and 1 type strain. The susceptibility of Arcanobacterium pyogenes to enrofloxacin, oxytetracycline and tilmicosin was determined by means of an agar disk diffusion test. The MICs of enrofloxacin, florfenicol, oxytetracycline and spiramycin were within the ranges of 0.125-0.5,1.0-2,0,2,0-4,0 and 4.0-8.0 I-'g/mt, respectively. This study has shown that resistance of MmmLC against enrofloxacin, florfenicol, oxytetracycline and spiramycin was negligible. All the field strains of A. pyogenes that were tested were susceptible to enrofloxacin, oxytetracycline and tilmicosin with mean inhibition zones of 30.6, 42.3 and 35.8 mm, respectively. Although there is lack of data on in vivo efficacy and in vitro MIC or inhibition zone diameter breakpoints of these antimicrobial drugs for MmmLC, the MIC results indicate that these 4 classes of antimicrobial drugs should be effective in the treatment of ulcerative balanitis and vulvitis in sheep in South Africa.

Item ID:	8983
Item Type:	Article (Research - C1)
ISSN:	0038-2809
Keywords:	Arcanobacterium pyogenes; Dorper sheep; minimum inhibitory concentrations; Mycoplasma mycoides mycoides; ulcerative balanoposthitis and vulvovaginitis
Date Deposited:	19 Mar 2010 04:37
FoR Codes:	07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070704 Veterinary Epidemiology @ 20% 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070707 Veterinary Microbiology (excl Virology) @ 80%
SEO Codes:	83 ANIMAL PRODUCTION AND ANIMAL PRIMARY PRODUCTS > 8399 Other Animal Production and Animal Primary Products > 839999 Animal Production and Animal Primary Products not elsewhere classified @ 100%
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