A Comprehensive Overview of Epidemiology, Pathogenesis and the Management of Herpes Labialis
Gopinath, Divya, Koe, Kim Hoe, Maharajan, Mari Kannan, and Panda, Swagatika (2023) A Comprehensive Overview of Epidemiology, Pathogenesis and the Management of Herpes Labialis. Viruses, 15 (1). 225.
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Abstract
Herpes labialis remains exceedingly prevalent and is one of the most common human viral infections throughout the world. Recurrent herpes labialis evolves from the initial viral infection by herpes simplex virus type 1 (HSV-1) which subsequently presents with or without symptoms. Reactivation of this virus is triggered by psychosocial factors such as stress, febrile environment, ultraviolet light susceptibility, or specific dietary inadequacy. This virus infection is also characterized by uninterrupted transitions between chronic-latent and acute-recurrent phases, allowing the virus to opportunistically avoid immunity and warrant the transmission to other vulnerable hosts simultaneously. This review comprehensively evaluates the current evidence on epidemiology, pathogenesis, transmission modes, clinical manifestations, and current management options of herpes labialis infections.
| Item ID: | 89766 |
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| Item Type: | Article (Research - C1) |
| ISSN: | 1999-4915 |
| Keywords: | antiviral agents, herpes labialis, management, prevention, treatments |
| Copyright Information: | © 2023 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| Date Deposited: | 04 May 2026 22:49 |
| FoR Codes: | 42 HEALTH SCIENCES > 4202 Epidemiology > 420299 Epidemiology not elsewhere classified @ 100% |
| SEO Codes: | 20 HEALTH > 2004 Public health (excl. specific population health) > 200499 Public health (excl. specific population health) not elsewhere classified @ 100% |
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