Zhao, Huan, Gordon, Catherine, and Bradbury, Richard S. (2025) Strongyloides fuelleborni. Trends in Parasitology, 42 (1). pp. 75-76.

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Abstract

[Extract] Strongyloides fuelleborni is the causative agent of one of the most neglected helminth infections of humans. S. fuelleborni subsp. fuelleborni, historically considered a rare zoonosis from Old World non-human primates (NHPs), has been increasingly reported in human communities from Africa and Asia. Evidence of interhuman transmission and emerging reports of human infections in Papua New Guinea indicate that this parasite likely has a wider range and prevalence than currently understood. S. fuelleborni subsp. kellyi is endemic to New Guinea where it has been associated with a fatal infantile enteropathy known as swollen belly syndrome (SBS). Molecular studies suggest that S. f. kellyi may be synonymous with the Asian-Pacific clade of S. f. fuelleborni. S. fuelleborni infection occurs via skin penetration of infective filariform larvae. Parasitic females reside in the small intestine where they reproduce parthenogenetically. Unlike Strongyloides stercoralis, not hatched larvae, but larvated eggs are shed in faeces.

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