Acta neurologica belgica regarding the manuscript entitled ‘Safety and efficacy of extended versus standard interval dosing of natalizumab in multiple sclerosis patients: a systematic review and meta-analysis’
Boggild, Mike, Mohammadpour, Zinat, van Eijk, Liza, and Williams, Lachlan (2025) Acta neurologica belgica regarding the manuscript entitled ‘Safety and efficacy of extended versus standard interval dosing of natalizumab in multiple sclerosis patients: a systematic review and meta-analysis’. Acta Neurologica Belgica, 126. pp. 269-270.
![[img]](https://researchonline.jcu.edu.au/style/images/fileicons/application_pdf.png) |
PDF (Published Version)
- Published Version
Restricted to Repository staff only |
Abstract
[Extract] We read the recent meta-analysis by Rabea et al. with interest [1]. The authors compare the safety and efficacy of extended interval dosing (EID) versus standard interval dosing (SID) of natalizumab in patients with multiple sclerosis (MS) [1]. While we agree that the data supports comparable clinical and radiological efficacy for SID and EID, we are concerned that the analysis does not reflect the probable relative safety of these dosing strategies.
| Item ID: | 88457 |
|---|---|
| Item Type: | Article (Commentary) |
| ISSN: | 2240-2993 |
| Copyright Information: | © The Author(s) under exclusive licence to Belgian Neurological Society 2025. |
| Date Deposited: | 21 Apr 2026 06:17 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320221 Psychiatry (incl. psychotherapy) @ 100% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200102 Efficacy of medications @ 100% |
| More Statistics |
Actions (Repository Staff Only)
 |
Item Control Page |