Novel association of ocular myasthenia gravis with Brown syndrome in an adult

Wang, Amy Tianyi, and Goodwin, Todd (2025) Novel association of ocular myasthenia gravis with Brown syndrome in an adult. Journal of Surgical Case Reports, 2025 (2). rjaf059.

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Abstract

Brown syndrome is an ocular misalignment disorder affecting the superior oblique tendon-trochlea complex. We report a case of a 45-year-old woman with protracted symptoms of presumed idiopathic Brown syndrome later diagnosed as ocular myasthenia gravis. Acquired Brown syndrome secondary to ocular myasthenia gravis has not previously been reported in the literature. Ocular myasthenia gravis should be considered a differential in any patient presenting with vertical strabismus presenting as Brown syndrome.

Item ID: 88337
Item Type: Article (Case Study)
ISSN: 2042-8812
Keywords: Brown syndrome, ocular motility, ocular myasthenia gravis
Copyright Information: © The Author(s) 2025. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Date Deposited: 10 Apr 2026 02:43
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3212 Ophthalmology and optometry > 321201 Ophthalmology @ 100%
SEO Codes: 20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 100%
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