Gregory, Harrison Haeata Keane, and Ferris, Baillie Ward Churchill (2025) Small bowel intussusception after Roux-en-Y gastric bypass – A case report. International Journal of Surgery Case Reports, 129. 111193.

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Abstract

Introduction and importance: Roux-en-Y gastric bypass (RYGB) is a common elective bariatric operation performed to facilitate weight loss in patients with obesity. Although generally associated with a low rate of late complications, intestinal intussusception can very rarely occur in patients who have undergone RYGB, with significant clinical consequences. This case reinforces the importance of prompt recognition and surgical intervention in cases of intussusception following RYGB, explores the proposed pathophysiology of intussusception, and highlights the options for surgical intervention. Case presentation: We report a case of a 52-year-old female presenting with a small bowel obstruction secondary to intussusception in the context of a RYGB performed 8-years previously. Computed tomography (CT) and diagnostic laparoscopy confirmed intussusception of a long segment of the biliopancreatic limb into the Roux limb through the jejuno-jejunal anastomosis. Unable to be reduced laparoscopically, the anastomosis was resected en bloc and refashioned. The patient recovered well, and reported no features of recurrence or other surgical complication at post-operative review. Clinical discussion: The aetiology of intussusception following RYGB is unclear, although hypotheses include interruption of duodenal pacemaker cells following transection of the small bowel and consequent development of ectopic jejunal pacemaker cells, increased mobility of the mesentery following extreme weight loss, or the jejunojejunal anastomosis functioning as a transition point. In cases of compromised bowel resection is essential, although the approach in cases of non-compromised bowel is less clear. Conclusion: The recognition of late RYGB complications is becoming increasingly important in the setting of the increasing prevalence of bariatric surgery. Intussusception is an infrequent but significant complication that requires urgent surgical intervention.

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