Mitigating dengue transmission in Africa: the need for Wolbachia-infected mosquitoes' rollout
Ogunlade, Samson T., Adekunle, Adeshina I., and McBryde, Emma S. (2024) Mitigating dengue transmission in Africa: the need for Wolbachia-infected mosquitoes' rollout. Frontiers in Public Health, 12. 1506072.
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Abstract
[Extract] Dengue fever is a mosquito-borne viral disease that poses a significant public health concern globally (1–3). The disease is primarily transmitted by Aedes aegypti mosquitoes and the range of clinical manifestations vary from flu-like symptoms (4, 5) to more serious conditions such as dengue haemorrhagic fever and dengue shock syndrome (6). The dengue virus (DENV) infects about 400 million people yearly, of which 50–100 million of those become symptomatic, with over 20,000 deaths (3).
Dengue notifications are increasing in Africa (1, 2). The continent's tropical and subtropical climatic conditions create a conducive breeding environment for mosquitoes and hence, contribute to the spread of the virus (1, 4, 7, 8). While recent statistics show that there were 15.7 million reported dengue infections in 2010, recent studies (1, 7, 8) show that dengue cases are on the rise in Africa. This situation presents an increasing threat to public health systems already under pressure from other infectious illnesses.
| Item ID: | 87497 |
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| Item Type: | Article (Commentary) |
| ISSN: | 2296-2565 |
| Keywords: | Africa, dengue, mosquitoes, rollout, Wolbachia |
| Copyright Information: | © 2024 Ogunlade, Adekunle and McBryde. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Date Deposited: | 09 Dec 2025 07:23 |
| FoR Codes: | 42 HEALTH SCIENCES > 4202 Epidemiology > 420207 Major global burdens of disease @ 100% |
| SEO Codes: | 20 HEALTH > 2004 Public health (excl. specific population health) > 200404 Disease distribution and transmission (incl. surveillance and response) @ 100% |
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