The 1% gift to humanity: The Human Genome Project II
Liu, Weibin, Li, Yan, Patrinos, George P., Xu, Shuhua, Thong, Meow Keong, Chen, Zhengming, Crawley, Francis P., Li, Liming, Ekmekci, Perihan Elif, Drmanac, Radoje, Cheong, Weiyang, Benamouzig, Robert, Nguyen, Quan, Volchkov, Pavel, Reichardt, Juergen K.V., Carninci, Piero, Majumder, Partha, Jin, Xin, Church, George, Wang, Jian, and Xu, Xun (2024) The 1% gift to humanity: The Human Genome Project II. Cell Research, 34 (11). pp. 747-750.
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Abstract
Upon announcing the completion of the Human Genome Project (HGP) in 2003, scientific leaders envisaged the transformative promise of the human genome for health and society.1 They anticipated genomics breakthroughs that could touch all of humanity and empower people to have longer healthier lives, ultimately creating a more prosperous society that also wields the human genome responsibly. Two decades on, human genomics now underpins the prospects of precision medicine and precision public health (Box 1). However, as further impactful advances increasingly depend on world-wide representation and collaboration, global-scale challenges that shackle progress must now be addressed. These are mainly economic, organizational, infrastructural, scientific, and Ethical, Legal and Social Implications (ELSI) challenges. Existing efforts lack coordination at the scale and scope required to overcome these challenges. In a time of heightened geopolitical uncertainty and legitimate citizen concern over the conscientious use of data and data-analysis methodologies, which include genomics big data and artificial intelligence (AI), we must draw inspiration from precedents where bold goals organized humanity to responsibly employ the best technologies and collaborative science toward their solution.2 In an era where intense corporate competition and geopolitical agendas threaten global collaboration, we must galvanize efforts to make precision medicine a universal gift — available and accessible to all of humanity for the generations to come.
| Item ID: | 87175 |
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| Item Type: | Article (Editorial) |
| ISSN: | 1748-7838 |
| Copyright Information: | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. |
| Date Deposited: | 20 Nov 2025 07:30 |
| FoR Codes: | 31 BIOLOGICAL SCIENCES > 3105 Genetics > 310506 Gene mapping @ 50% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3205 Medical biochemistry and metabolomics > 320505 Medical biochemistry - nucleic acids @ 50% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200104 Prevention of human diseases and conditions @ 50% 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 50% |
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