Preclinical ALM (Adenosine, Lidocaine, Magnesium): Navigating Doubts
Biros, Erik, Birosova, Eva, and Moran, Corey S. (2024) Preclinical ALM (Adenosine, Lidocaine, Magnesium): Navigating Doubts. Mayo Clinic Proceedings, 99 (11). pp. 1838-1839.
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Abstract
[Extract] Under the guidance of Geoffrey P. Dobson, a team of researchers has made significant preclinical strides in exploring the use of adenosine, lidocaine, and magnesium (ALM) for treating various clinical conditions. However, as its applications diversify, the effectiveness of ALM comes into question. This letter revisits the origins of ALM, its early use in experimental hemorrhage, and its recent use in experimental anterior cruciate ligament (ACL) surgery scenarios to provide insight into its design and clinical usefulness.
| Item ID: | 87171 |
|---|---|
| Item Type: | Article (Short Note) |
| ISSN: | 1942-5546 |
| Copyright Information: | © 2024 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. |
| Date Deposited: | 07 May 2026 06:07 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3201 Cardiovascular medicine and haematology > 320101 Cardiology (incl. cardiovascular diseases) @ 100% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100% |
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