Esmaili, S., George, J., and Hebbard, L. (2011) The role of adiponectin in NAFLD progression. Journal of Gastroenterology and Hepatology, 26 (s4). p. 9.

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Abstract

Lipid toxicity and inflammation are important components in the transition of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH). Factors such as reduced adiponectin have been associated with liver steatosis and inflammation. However, the molecular events underlying NAFLD progression in respect of adiponectin have not been thoroughly investigated. Recent data suggests that free cholesterol sensitizes hepatocytes to TNF-alpha and Fas-induced apoptosis and steatohepatitis development. In this study we examined the association of adiponectin and cholesterol to NAFLD progression.

Item ID:	86250
Item Type:	Article (Abstract)
ISSN:	1440-1746
Copyright Information:	© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing.
Date Deposited:	24 Jul 2025 23:55
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320209 Gastroenterology and hepatology @ 100%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 100%
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