Brown, Darren, Tariq, Shema, Boffito, Marta, Asboe, David, Milinkovic, Ana, Nwokolo, Nneka, Flavell, Carol, Strachan, Sophie, Avery, Lisa, O'Brien, Kelly, and Harding, Richard (2025) Psychometric properties of the Episodic Disability Questionnaire (EDQ) among women living with HIV in the UK: a self-report repeated measure study. HIV Medicine, 26 (S2). A121. p. 92.

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Abstract

Background: Disability is an important health-related outcome as people age with HIV and multimorbidity. The Episodic Disability Questionnaire (EDQ) measures the presence, severity, and episodic nature of disability across six domains. We assessed EDQ properties among women living with HIV. Method: Participants were recruited from the Positive Transitions Through the Menopause (PRIME) study, completing EDQ (2 timepoints 1 week apart), three criterion measures (WHODAS 2.0, EQ-5-DL, Work and Social Adjustment Scale), and demographic questionnaire electronically. We assessed (1) internal consistency; Cronbach alpha; >0.8 (2) precision of measurement; minimal detectable change (MDC) 95% (3) construct validity; >75% a priori (6 primary, 53 secondary) hypotheses met for EDQ-criterion correlations (4) test–retest reliability (intra-class coefficient (ICC); >0.7). Disability prevalence was measured with WHODAS 2.0 (moderate threshold) and UK Equality Act Disability Definition (severe threshold). Results: One hundred and four participants from seven NHS clinics in England completed questionnaires, of which n = 93 (89%) completed EDQ approximately one week later. All participants were female sex. Median age and duration living with HIV were 56 years (IQR 54–58) and 23 years (IQR 18–27) respectively. Ethnicity Black, Black British, Caribbean or African was n = 67 (65%),anti-retroviral therapy n = 102 (99%), most recent viral load <50 copies/mL n = 80 (89%), and living with multi-morbidity [2 or more comorbidities] n = 89 (86%). Cronbach's alpha ranged from 0.83 (social domain) to 0.92 (daily activities domain). Highest precision was in daily activities domain (MDC95%: 6.10), with lowest precision in mental–emotional domain (MDC95%: 11.52). All primary (n = 6, 100%) and 77% secondary (n = 41) construct validity hypotheses were met. ICC ranged from 0.70 (physical domain) to 0.91 (daily activities domain). Disability prevalence ranged from 79.81% (95%CI 70.57,86.79) moderate to 23.30% (15.78, 32.86) severe disability. Conclusion: The EDQ possesses internal consistency, construct validity, and test–retest reliability, with varied precision when administered electronically with women living with HIV in the UK. Within the UK Equality Act, 23% of the sample is classified as having a disability. Given the measurement properties, and more people ageing with HIV, multimorbidity and disability, the EDQ can be used for research and clinical practice to measure disability and evaluate interventions among women living with HIV.

Item ID:	85298
Item Type:	Article (Abstract)
ISSN:	1468-1293
Keywords:	HIV, Reliability, Validity, Episodic disability
Additional Information:	Presented at the BHIVA Spring Conference, Brighton, UK, 23-25 April 2025.
Funders:	British HIV Association
Projects and Grants:	BHIVA Research Award 2020
Date Deposited:	30 Apr 2025 22:55
FoR Codes:	42 HEALTH SCIENCES > 4201 Allied health and rehabilitation science > 420109 Rehabilitation @ 100%
SEO Codes:	20 HEALTH > 2005 Specific population health (excl. Indigenous health) > 200509 Women's and maternal health @ 100%
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