Pierce, Doris Renate (2022) Experimental hookworm infection in humans with metabolic disease. PhD thesis, James Cook University.

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Abstract

Doris Pierce investigated experimental hookworm infection in humans with metabolic disease. She found that infection with 20 hookworm larvae significantly improved insulin resistance that was associated with body mass reductions in this cohort. The results confirm the protective role of worm infection as a therapeutic tool against metabolic disease.

Item ID:	85260
Item Type:	Thesis (PhD)
Keywords:	Hookworm, metabolic disease, immunology, microbiology
Related URLs:	https://researchonline.jcu.edu.au/61204/
Copyright Information:	Copyright © 2022 Doris Renate Pierce
Additional Information:	One publication arising from this thesis is stored in ResearchOnline@JCU, at time of processing. Please see the Related URLS. The publication is: [Chapter 2] Pierce, Doris, Merone, Lea, Lewis, Chris, Rahman, Tony, Croese, John, Loukas, Alex, McDonald, Malcolm, Giacomin, Paul, and McDermott, Robyn (2019) Safety and tolerability of experimental hookworm infection in humans with metabolic disease: study protocol for a phase 1b randomised controlled clinical trial. BMC Endocrine Disorders, 19. 136.
Date Deposited:	29 Apr 2025 05:01
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320407 Innate immunity @ 30% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320404 Cellular immunology @ 40% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320704 Medical parasitology @ 30%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 100%
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