Development of adjuvant therapy to treat biofilm-related staphylococcus aureus prosthetic joint infection
Pant, Narayan (2022) Development of adjuvant therapy to treat biofilm-related staphylococcus aureus prosthetic joint infection. PhD thesis, James Cook University.
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Abstract
Narayan Pant studied the efficacy of savirin and ticagrelor to treat prosthetic joint infection (PJI) using a mouse model. Both the molecules tested were effective in reducing PJI. These results can be used to develop new therapy for PJI treatment.
| Item ID: | 85119 |
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| Item Type: | Thesis (PhD) |
| Keywords: | Prosthetic joint infection, adjuvant therapy, biofilm |
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| Copyright Information: | Copyright © 2022 Narayan Pant |
| Additional Information: | Two publications arising from this thesis are stored in ResearchOnline@JCU, at time of processing. Please see the Related URLS. The publications are: [Chapter 2] Pant, Narayan, Miranda-Hernandez, Socorro, Rush, Catherine, Warner, Jeffrey, and Eisen, Damon P. (2022) Non-Antimicrobial Adjuvant Therapy Using Ticagrelor Reduced Biofilm-Related Staphylococcus aureus Prosthetic Joint Infection. Frontiers in Pharmacology, 13. 927783. [Chapter 7] Pant, Narayan, Wallis, Steven C., Roberts, Jason A., and Eisen, Damon P. (2022) In vitro effect of synovial fluid from patients undergoing arthroplasty surgery on MRSA biofilm formation. Journal of Antimicrobial Chemotherapy, 77 (4). pp. 1041-1044. |
| Date Deposited: | 14 Apr 2025 23:46 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320701 Medical bacteriology @ 100% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100% |
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