Bradley, John, Ogouyèmi‑Hounto, Aurore, Cornélie, Sylvie, Fassinou, Jacob, de Tove, Yolande Sissinto Savi, Adéothy, Adicath Adéola, Tokponnon, Filémon T., Makoutode, Patrick, Adechoubou, Alioun, Legba, Thibaut, Houansou, Telesphore, Kinde‑Gazard, Dorothée, Akogbeto, Martin C., Massougbodji, Achille, Knox, Tessa, Donnelly, Martin, and Kleinschmidt, Immo (2017) Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin. Malaria Journal, 16. 225.

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Abstract

Background: Malaria control is heavily reliant on insecticides, especially pyrethroids. Resistance of mosquitoes to insecticides may threaten the effectiveness of insecticide-based vector control and lead to a resurgence of malaria in Africa.

Methods: In 21 villages in Southern Benin with high levels of insecticide resistance, the resistance status of local vectors was measured at the same time as the prevalence of malaria infection in resident children.

Results: Children who used LLINs had lower levels of malaria infection [odds ratio = 0.76 (95% CI 0.59, 0.98, p = 0.033)]. There was no evidence that the effectiveness of nets was different in high and low resistance locations (p = 0.513). There was no association between village level resistance and village level malaria prevalence (p = 0.999).

Conclusions: LLINs continue to offer individual protection against malaria infection in an area of high resistance. Insecticide resistance is not a reason to stop efforts to increase coverage of LLINs in Africa.

Item ID:	84677
Item Type:	Article (Research - C1)
ISSN:	1475-2875
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Copyright Information:	© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/+publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Date Deposited:	19 Feb 2025 22:55
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