Diabetes Mellitus and the Kidneys

Gal, Arnon, and Burchell, Richard K. (2023) Diabetes Mellitus and the Kidneys. Veterinary Clinics of North America - Small Animal Practice, 53 (3). pp. 565-580.

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Abstract

Diabetic kidney disease (DKD) is a chronic progressive kidney disease that is the most common cause of end-stage renal failure in people in the western world.1 DKD results from multifactorial pathophysiological mechanisms and clinically manifests with proteinuria, subsequent progressive decline in glomerular filtration rate (GFR), and ultimately progression to end-stage renal disease.2 There is minimal published information about DKD in companion animals in the veterinary literature. The first part of this review will focus on the pathophysiology of DKD, derived mainly from the human medical literature and rodent models of DKD. Wherever there was corresponding information relevant to companion animals, we mentioned it. The second part of this review focuses on the limited veterinary literature that loosely supports the existence of DKD as a clinical entity in companion animals.

Item ID: 83017
Item Type: Article (Research - C1)
ISSN: 1878-1306
Copyright Information: © 2023 Elsevier Inc. All rights reserved.
Date Deposited: 24 Jun 2024 23:30
FoR Codes: 30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300907 Veterinary medicine (excl. urology) @ 100%
SEO Codes: 20 HEALTH > 2099 Other health > 209999 Other health not elsewhere classified @ 100%
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