Drever, N., Hutson, J.M., Southwell, B.R., and Grover, S.R. (2012) Vaginal Agenesis, the Hymen, and Associated Anomalies. Journal of Pediatric and Adolescent Gynecology, 25 (1). pp. 54-58.

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Abstract

Study Objectives: Review anomalies in patients with vaginal agenesis. In particular, to clarify the impact of an absent hymen on the presence of other anomalies; on the success of creating a vagina with dilators; and on sexual function outcomes.

Design: Retrospective medical record review; questionnaire on sexual function.

Setting: Gynecology service at a children’s hospital and the practice of 1 gynecologist.

Participants: All patients with vaginal agenesis were identified from the databases, as well as the subgroup in which hymenal status was known.

Outcome Measures: Data regarding hymen, renal, skeletal, cardiac, and other anomalies; for women who had a neovagina, the technique used to create a functional vagina.

Results: Of 69 females (age range 2–70 years), renal tract anomalies (43.3%), vertebral anomalies (29%), cardiac anomalies (14.5%), and syndromes including Klippel-Feil (7%) and MURCS association (7%) were identified. Where hymenal status was known (n = 47), 31 were normal, and 16 had an absent hymen. Where the hymen was absent, renal agenesis was increased (odds ratio = 13.5, P < .001). There was no association between other anomalies and an absent hymen, or between the various anomalies. For women without a hymen, the likelihood of failing dilation therapy was increased (odds ratio = 21.7; P < .01].

Conclusion: An absent hymen makes renal agenesis more likely and increases the likelihood that dilator techniques will fail. This condition appears to be associated with reports of long-term problems with poor lubrication that are potentially related to the absence of the peri-hymenal Bartholin’s glands.

Item ID:	82922
Item Type:	Article (Research - C1)
ISSN:	1873-4332
Copyright Information:	© 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc.
Date Deposited:	18 Jun 2024 03:23
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3215 Reproductive medicine > 321502 Obstetrics and gynaecology @ 100%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 100%
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