Kendell-Wall, Rachael, Nguyen, Jennifer-Thuy, Salleras, Fauve, Singh Kamboj, Amandeep, Aimee Diwen Tan, Serene, Manish Trivedi, Vaidehi, Martins de Mello-Neto, Joao, and Rodrigues Amaral, Rodrigo (2024) Antimicrobial efficacy of Odontopaste in endodontics: a systematic review. Evidence Based Dentistry. (In Press)

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Abstract

AIM: To evaluate the efficacy of Odontopaste in reducing the microbial load in endodontics compared to other intracanal medicaments.

MATERIALS AND METHODS: The literature was electronically searched on PubMed, Google Scholar, Scopus, Ovid Medline and Web of Science. In-vitro, ex-vivo and in-vivo studies that evaluated the antimicrobial efficacy of Odontopaste were included. The risk of bias was assessed using the Quality Assessment Tool for In Vitro Studies.

RESULTS: A total of four in-vitro studies were included in the systematic review. One study showed that Odontopaste had significantly more microbial cell growth on roots in all dentine depths compared to other medicaments or test agents. Another study found that Odontopaste significantly decreased colony-forming units compared to propolis and chlorhexidine. Further results showed that Odontopaste did not significantly decrease microbial numbers when used in isolation. Additionally, combining Odontopaste and calcium hydroxide did not enhance the effectiveness of calcium hydroxide. The studies had a medium to high risk of bias.

CONCLUSION: There is insufficient high-quality evidence to assess the antimicrobial efficacy of Odontopaste compared to other intracanal medicaments. Further research is required to determine Odontopaste’s efficacy as an antimicrobial medicament in endodontics.

Item ID:	82669
Item Type:	Article (Research - C1)
ISSN:	1476-5446
Keywords:	Endodontics; odontopaste; root canal treatment
Copyright Information:	Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Date Deposited:	07 May 2024 23:36
FoR Codes:	42 HEALTH SCIENCES > 4299 Other health sciences > 429999 Other health sciences not elsewhere classified @ 100%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200102 Efficacy of medications @ 50% 20 HEALTH > 2099 Other health > 209999 Other health not elsewhere classified @ 50%
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