Adamu, Andrew Musa, McNabb, Leanne, Adikwu Adikwu, Alex, Jibril Jibril, Yakubu, Idoko Idoko, Sunday, Turaki, Aliyu Usman, Abalaka, Samson Eneojo, Edeh, Richard Emmanuel, Egwu, Godwin Onyemaechi, Adah, Mohammed Ignatius, and Halpin, Kim (2022) Henipavirus sero-surveillance in horses and pigs from Northern Nigeria. Frontiers in Virology, 2. 929715.

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Abstract

Hendra virus and Nipah virus are considered to be emerging viruses and cause severe zoonotic diseases, which occur in humans who have had close contact with horses and pigs in Australia and Asia, respectively. Both viruses belong to the genus Henipavirus. Although there are large populations of horses and pigs in northern Nigeria, no previous studies in this region have investigated henipavirus sero-surveillance in horses and pigs using the gold standard test, the serum neutralization test (SNT). A total of 536 apparently healthy horses and 508 apparently healthy pigs were sampled in northern Nigeria in 2018. Serum samples were tested for Hendra virus and Nipah virus-specific antibodies using either the Henipavirus Luminex binding assays for horses or the Hendra virus Competitive ELISA and Nipah virus Indirect ELISA for pigs as initial screening tests, followed by the confirmatory Hendra and Nipah virus SNT for both species, according to accredited protocols at the Australian Centre for Disease Preparedness. Although some horse and pig samples crossed-reacted or reacted weakly in the screening test, confirmatory SNT for all of them proved negative. This study reveals the absence of Hendra and Nipah antibodies in horses and pigs in northern Nigeria, which is consistent with the absence of observable disease in the field. However, the continuous inter and intra-trans-boundary animal movement and trade in Nigeria calls for the continuous evaluation of the henipavirus status of susceptible animals to safeguard both animal and human health.

Item ID:	82662
Item Type:	Article (Research - C1)
ISSN:	2673-818X
Copyright Information:	Copyright © 2022 Adamu, McNabb, Adikwu, Jibril, Idoko, Turaki, Abalaka, Edeh, Egwu, Adah and Halpin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Date Deposited:	07 May 2024 22:55
FoR Codes:	30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300914 Veterinary virology @ 50% 30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300905 Veterinary epidemiology @ 50%
SEO Codes:	10 ANIMAL PRODUCTION AND ANIMAL PRIMARY PRODUCTS > 1004 Livestock raising > 100410 Pigs @ 30% 10 ANIMAL PRODUCTION AND ANIMAL PRIMARY PRODUCTS > 1004 Livestock raising > 100406 Horses @ 30% 20 HEALTH > 2004 Public health (excl. specific population health) > 200404 Disease distribution and transmission (incl. surveillance and response) @ 40%
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