Detection and genetic characterization of orf virus from sheep and goats in Nigeria

Onoja, B.A., Adamu, A.M., Anyang, A.O., Oragwa, A.O., Omelza, G.K., Olabode, O.H., and Horwood, P.F. (2024) Detection and genetic characterization of orf virus from sheep and goats in Nigeria. Tropical Animal Health and Production, 56. 77.

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Orf is a contagious, viral epitheliotropic disease of small ruminants. We investigated the molecular epidemiology of orf virus (ORFV) in breeds of small ruminants to determine the evolutionary diversity in Nigeria. Out of 54 small ruminants screened, the number of animals that were positive for ORFV in the three locations were 25. The distribution of positive animals by location were FCT 45.0% (n = 9/20), Oyo State 42.9% (6/14), and Plateau State 50.0% (n = 10/20). ORFV sequences from this study clustered with viruses detected in Taiwan, Iran, USA, and France. Our findings highlight the risk of transmission across geographic boundaries in Nigeria and West Africa, and reinforces the need for increased surveillance to prevent and control spread. Comprehensive characterization of ORFV in small ruminants as well as in humans in Nigeria is required to better elucidate the epidemiological dynamics and the virus evolution.

Item ID: 82542
Item Type: Article (Research - C1)
ISSN: 1573-7438
Copyright Information: © The Author(s), under exclusive licence to Springer Nature B.V. 2024.
Date Deposited: 03 Apr 2024 22:58
FoR Codes: 30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300914 Veterinary virology @ 100%
SEO Codes: 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280101 Expanding knowledge in the agricultural, food and veterinary sciences @ 100%
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