Ketamine-Assisted Psychotherapy Provides Lasting and Effective Results in the Treatment of Depression, Anxiety, and Post-Traumatic Stress Disorder at 3 and 6 Months: Findings from a Large Retrospective Effectiveness Study

Yermus, Ryan, Bottos, John, Bryson, Nathan, De Leo, Joseph A., Earleywine, Mitch, Hackenburg, Emily, Kennedy, Sidney, Kezemidis, Martha, Kratina, Sarah, McMaster, Robert, Medrano, Ben, Mina, Monica, Morisano, Dominique, Muench, Michael, Pillai, Sabana, Scharlach, Randall, Setlur, Varun, Verbora, Michael, Wolfson, Elizabeth, Zaer, Nabid, and Lo, Chris (2024) Ketamine-Assisted Psychotherapy Provides Lasting and Effective Results in the Treatment of Depression, Anxiety, and Post-Traumatic Stress Disorder at 3 and 6 Months: Findings from a Large Retrospective Effectiveness Study. Psychedelic Medicine. (In Press)

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DOI: 10.1089/psymed.2023.0021

View at Publisher Website: https://doi.org/10.1089/psymed.2023.0021

Abstract

Importance: Ketamine-assisted psychotherapy (KAP) is an emerging treatment option to alleviate treatment-resistant affective disorders, but its long-term effectiveness remains unclear.

Objective: To examine the treatment effects of KAP on anxiety, depression, and post-traumatic stress disorder (PTSD) at 1, 3, and 6 months post-treatment.

Design, Setting, and Participants: This retrospective effectiveness study included self-reported outcomes from adults with a history of major depressive disorder, generalized anxiety disorder (GAD), or PTSD who had not responded to prior treatment interventions and received KAP administered across 11 Field Trip Health clinics in North America between March 13, 2020, and June 16, 2022. The evaluable sample sizes were 346 and 94 participants at 3 and 6 months, respectively, representing loss to follow-up rates of 82% and 95%.


Item ID:	81981
Item Type:	Article (Research - C1)
ISSN:	2831-4433
Copyright Information:	© Mary Ann Liebert, Inc
Date Deposited:	13 May 2024 23:45
FoR Codes:	52 PSYCHOLOGY > 5203 Clinical and health psychology > 520399 Clinical and health psychology not elsewhere classified @ 50% 42 HEALTH SCIENCES > 4206 Public health > 420699 Public health not elsewhere classified @ 30% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3214 Pharmacology and pharmaceutical sciences > 321402 Clinical pharmacology and therapeutics @ 20%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100%
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