Parasitic infection surveillance in Mississippi delta children
Bradbury, Richard S., Arguello, Irene, Lane, Meredith, Cooley, Gretchen, Handali, Sukwan, Dimitrova, Silvia D., Nascimento, Fernanda S., Jameson, Sam, Hellmann, Kathryn, Tharp, Michelle, Byers, Paul, Montgomery, Susan P., Haynie, Lisa, Kirmse, Brian, Pilotte, Nils, Williams, Steven A., and Hobbs, Charlotte V. (2020) Parasitic infection surveillance in Mississippi delta children. American Journal of Tropical Medicine and Hygiene, 103 (3). pp. 1150-1153.
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Abstract
Some recent studies suggest ongoing transmission of parasitic diseases in the American South; however, surveys in Mississippi children are lacking. We enrolled 166 children (median age 8 years, range 4–13 years) from the Mississippi Delta region and carried out multi-parallel real-time polymerase chain reaction (PCR) for Necator americanus, Ascaris lumbricoides, and Strongyloides stercoralis on their stool samples. Dried blood spots were obtained for multiplex serology antibody detection. Of 166 children, all reported having flushable toilets, 11% had soil exposure, and 34% had a pet dog or cat. None had prior diagnosis or treatment of parasitic disease. Multi-parallel real-time PCRs were negative on the 89 stool DNA extracts available for testing. Dried blood spot testing of all 166 children determined the seroprevalence of IgG antibodies to Toxocara spp. (3.6%), Cryptosporidium (2.4%), S. stercoralis, Fasciola hepatica, and Giardia duodenalis (all 0%). In conclusion, parasitic infections and exposure were scarce in this population. Larger studies of at-risk populations are needed.
Item ID: | 81828 |
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Item Type: | Article (Research - C1) |
ISSN: | 1476-1645 |
Copyright Information: | © 2020 by The American Society of Tropical Medicine and Hygiene |
Date Deposited: | 20 Jun 2024 00:22 |
FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320704 Medical parasitology @ 100% |
SEO Codes: | 20 HEALTH > 2004 Public health (excl. specific population health) > 200404 Disease distribution and transmission (incl. surveillance and response) @ 80% 20 HEALTH > 2005 Specific population health (excl. Indigenous health) > 200508 Rural and remote area health @ 20% |
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