Biomarker discovery for EBV-associated cancers and tuberculosis
Sarathkumara, Seekkuge Yomani Dilukshi (2022) Biomarker discovery for EBV-associated cancers and tuberculosis. PhD thesis, James Cook University.
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Abstract
Yomani Sarathkumara studied latent infections associated with Epstein-Barr virus and Mycobacterium tuberculosis, the causative agent of tuberculosis. She identified biomarkers using two synergistic platforms of protein expression (protein array) and gene expression (transcriptomics) to extend understanding of immune responses at the humoral and molecular level in multiple disease models associated with latent infections.
| Item ID: | 81322 |
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| Item Type: | Thesis (PhD) |
| Keywords: | Epstein-Barr virus, mycobacterium tuberculosis, tuberculosis, biomarkers, protein expression, gene expression, immune responses, natural killer/T-cell lymphoma, Hodgkin lymphoma |
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| Copyright Information: | Copyright © 2022 Seekkuge Yomani Dilukshi Sarathkumara |
| Additional Information: | Embargoed until 31 May 2024 Two publications arising from this thesis are stored in ResearchOnline@JCU, at the time of processing. Please see the Related URLs. The publications are: [Chapter 2] Liu, Zhiwei, Sarathkumara, Yomani, Chan, John K.C., Kwong, Yok-Lam, Lam, Tai Hing, Ip, Dennis Kai Ming, Chiu, Brian C.-H., Xu, Jun, Su, Yu-Chieh, Proietti, Carla, Cooper, Martha, Yu, Kelly J., Bassig, Bryan, Liang, Raymond, Hu, Wei, Ji, Bu-Tian, Coghill, Anna E., Pfeiffer, Ruth M., Hildesheim, Allan, Rothman, Nathaniel, Doolan, Denise, and Lan, Qing (2021) Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma. Scientific Reports, 11. 23664 [Chapter 6] Sarathkumara, Yomani D., Browne, Daniel J., Kelly, Ashton M., Pattinson, David J., Rush, Catherine M., Warner, Jeffrey, Proietti, Carla, and Doolan, Denise L. (2022) The Effect of Tropical Temperatures on the Quality of RNA Extracted from Stabilized Whole-Blood Samples. International Journal of Molecular Sciences, 23 (18). 10609 |
| Date Deposited: | 17 Jan 2024 02:52 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320705 Medical virology @ 60% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3299 Other biomedical and clinical sciences > 329999 Other biomedical and clinical sciences not elsewhere classified @ 40% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200104 Prevention of human diseases and conditions @ 60% 20 HEALTH > 2001 Clinical health > 200199 Clinical health not elsewhere classified @ 40% |
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