Fully Automated CAD System for Lung Cancer Detection and Classification Using 3D Residual U-Net with multi-Region Proposal Network (mRPN) in CT Images

Masood, Anum, Naseem, Usman, and Nasim, Mehwish (2023) Fully Automated CAD System for Lung Cancer Detection and Classification Using 3D Residual U-Net with multi-Region Proposal Network (mRPN) in CT Images. In: Lecture Notes in Computer Science. pp. 29-39. From: CaPTion: 2nd International Workshop on Cancer Prevention through Early Detection, 12 October 2023, Vancouver, Canada.

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Abstract

Lung cancer is one of the leading causes of mortality worldwide. The survival rate of lung cancer depends on its timely detection and diagnosis. For pulmonary cancer detection, numerous Computer-Assisted Diagnosis (CADx) systems have been developed that use the CT scan imaging modality. Recent advancement in deep learning techniques has enabled these CADx to automatically model high-level abstractions in CT-Scan images using a multi-layered Convolutional Neural Network (CNN). Our proposed CAD system comprises 3D residual U-Net for nodule detection. Initially, the 3D residual U-Net resulted in false positive results; therefore, a multi-Region Proposal Network (mRPN) was proposed for the improvement of nodule detection. The detected nodules are assigned a probability of malignancy. Furthermore, each detected nodule is classified into four classes based on its respective malignancy score. Extensive experimental results illustrate the effectiveness of our 3D residual U-Net model. These results demonstrate the exceptional detection performance achieved by our proposed model with a sensitivity of 97.65% and an average classification accuracy of 96.37%. Performance analysis demonstrates the potential of the proposed CAD system for the detection and classification of lung nodules with high efficiency and precision.

Item ID: 81079
Item Type: Conference Item (Research - E1)
ISBN: 9783031453496
Keywords: 3D U-Net, CAD systems, CT image, Deep Learning, Lung cancer
Copyright Information: © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Date Deposited: 19 Mar 2024 23:56
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3211 Oncology and carcinogenesis > 321102 Cancer diagnosis @ 50%
46 INFORMATION AND COMPUTING SCIENCES > 4601 Applied computing > 460102 Applications in health @ 20%
46 INFORMATION AND COMPUTING SCIENCES > 4603 Computer vision and multimedia computation > 460306 Image processing @ 30%
SEO Codes: 22 INFORMATION AND COMMUNICATION SERVICES > 2204 Information systems, technologies and services > 220403 Artificial intelligence @ 100%
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