Horizon scanning the application of probiotics for wildlife
Garcias-Bonet, Neus, Roik, Anna, Tierney, Braden, García, Francisca C., Villela, Helena D.M., Dungan, Ashley M., Quigley, Kate M., Sweet, Michael, Berg, Gabriele, Gram, Lone, Bourne, David G., Ushijima, Blake, Sogin, Maggie, Hoj, Lone, Duarte, Gustavo, Hirt, Heribert, Smalla, Kornelia, Rosado, Alexandre S., Carvalho, Susana, Thurber, Rebecca Vega, Ziegler, Maren, Mason, Christopher E., van Oppen, Madeleine J.H., Voolstra, Christian R., and Peixoto, Raquel S. (2024) Horizon scanning the application of probiotics for wildlife. Trends in Microbiology, 32 (3). pp. 252-269.
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Abstract
The provision of probiotics benefits the health of a wide range of organisms, from humans to animals and plants. Probiotics can enhance stress resilience of endangered organisms, many of which are critically threatened by anthropogenic impacts. The use of so-called ‘probiotics for wildlife’ is a nascent application, and the field needs to reflect on standards for its development, testing, validation, risk assessment, and deployment. Here, we identify the main challenges of this emerging intervention and provide a roadmap to validate the effectiveness of wildlife probiotics. We cover the essential use of inert negative controls in trials and the investigation of the probiotic mechanisms of action. We also suggest alternative microbial therapies that could be tested in parallel with the probiotic application. Our recommendations align approaches used for humans, aquaculture, and plants to the emerging concept and use of probiotics for wildlife.
Item ID: | 80916 |
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Item Type: | Article (Research - C1) |
ISSN: | 1878-4380 |
Keywords: | amphibians, bats, bees, biodiversity decline, conservation, coral, emergent interventions, microbial therapies, negative control, placebo, probiotics, rehabilitation, restoration, wildlife |
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Copyright Information: | © 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). |
Funders: | Australian Research Council (ARC) |
Projects and Grants: | ARC Laureate Fellowship FL180100036, ARC Discovery Project DP210100630 |
Date Deposited: | 31 Oct 2023 03:26 |
FoR Codes: | 31 BIOLOGICAL SCIENCES > 3107 Microbiology > 310703 Microbial ecology @ 100% |
SEO Codes: | 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280111 Expanding knowledge in the environmental sciences @ 100% |
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