Beena, S., Rao, K. N. S., and Pai, M. R. S. M. (2002) Comparative evaluation of efficacy and safety profile of three anti-tuberculous regimens in Mangalore. Indian Journal of Medical Sciences, 56 (7). pp. 315-320.

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Abstract

The aim of our study was to evaluate and compare the therapeutic efficacy & safety profile of three different antituberculous regimens for pulmonary tuberculosis. The study sample size included 90 newly diagnosed, sputum positive patients of pulmonary. tuberculosis. 30 each from different groups. The parameters studied were, therapeutic efficacy included weight gain, cough, sputum examination and safety profile: nausea, vomiting, anorexia, gastritis, hepatitis, jaundice diarrhoea, rashes, dizziness, tingling & numbness, flu like symptoms & joint aches. Group-I showed statistically significant weight gain when compared to Group-II. Improvement in cough and conversion to smear negative were seen in 100% of patients in Group-I, 83.3% of patients in Group-II and 93.3% of patients in Group-III. Therapeutic efficacy was highest with Group I regimen, followed by Group III and Group II which was least efficacious. Group II also registered; the maximum cost and highest incidence of adverse effects.

Item ID:	78747
Item Type:	Article (Research - C1)
ISSN:	1998-3654
Copyright Information:	© Copyright Indian Journal of Medical Sciences – All rights reserved.
Date Deposited:	14 Nov 2023 01:02
FoR Codes:	42 HEALTH SCIENCES > 4206 Public health > 420603 Health promotion @ 100%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200102 Efficacy of medications @ 100%
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