IgE-mediated Anisakis allergy in children
Pontone, Matteo, Giovannini, Mattia, Barni, Simona, Mori, Francesca, Venturini, Elisabetta, Galli, Luisa, Valleriani, Claudia, De las Vecillas, Leticia, Sackesen, Cansin, Lopata, Andreas Ludwig, and Buyuktiryaki, Betul (2023) IgE-mediated Anisakis allergy in children. Allergologia et Immunopathologia, 51 (1). pp. 98-109.
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Abstract
Anisakids are nematodes responsible for different clinical patterns in humans. The well-known human-infecting Anisakis species include members of the Anisakis simplex (AS) complex. Humans usually contract anisakiasis through ingestion of raw or undercooked seafood containing Anisakis larvae. Once Anisakis has been ingested, patients may develop disease driven directly by Anisakis larvae and/or by allergic reaction due to this nematode. The capability of inducing allergic reactions depends on the expression of specific antigens by nematodes and host factors. This study aims to resume actual knowledge about AS and Anisakiasis with regard to epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment. Particular attention is paid to Anisakis allergens and their cross-reactivity on available diagnostic methods, and defining a diagnostic pathway for Anisakis allergy. Because only a few data are available in the literature about pediatric population, we focus on this group of patients specifically.
Item ID: | 78571 |
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Item Type: | Article (Research - C1) |
ISSN: | 1578-1267 |
Keywords: | Allergen, Anisakis allergy, Basophil activation test, Component-resolved diagnosis, Fish parasite, Immunoglobulin e, Infection, Management, Oral food challenge, Pediatrics, Skin prick test |
Copyright Information: | Copyright: Pontone M, et al. This open access article is licensed under Creative Commons Attribution 4.0 International (CC BY 4.0). http://creativecommons.org/ |
Date Deposited: | 09 Jan 2024 00:50 |
FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320401 Allergy @ 70% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320704 Medical parasitology @ 30% |
SEO Codes: | 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100% |
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