A resurgence and re-emergence of diphtheria in Nigeria, 2023

Adegboye, Oyelola A., Alele, Faith O., Pak, Anton, Castellanos, Maria E., Abdullahi, Mohammed, Okeke, Malachy I., Emeto, Theophilus I., and McBryde, Emma S. (2023) A resurgence and re-emergence of diphtheria in Nigeria, 2023. Therapeutic Advances in Infectious Disease, 10.

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Abstract

[Extract] Diphtheria is a highly contagious vaccine-preventable bacterial infection caused by Corynebacterium diphtheriae that primarily infects the throat (pharynx and tonsils) and nose. The bacterium has an estimated basic reproduction number of 1.7–4.3. Although diphtheria is treatable if detected early, it can lead to severe complications such as respiratory failure, heart problems and even deaths (case-fatality ratio among untreated, never vaccinated cases 28.8–29.2%). It remains a health problem in low-resource countries, particularly where vaccination uptake and coverage are low and where sanitation conditions remain poor.

Item ID: 77997
Item Type: Article (Commentary)
ISSN: 2049-937X
Copyright Information: Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Date Deposited: 07 Jun 2023 00:01
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320211 Infectious diseases @ 50%
42 HEALTH SCIENCES > 4206 Public health > 420699 Public health not elsewhere classified @ 50%
SEO Codes: 20 HEALTH > 2002 Evaluation of health and support services > 200204 Health inequalities @ 100%
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