Ramezani Tehrani, F., Minooee, S., Simbar, M., and Azizi, F. (2013) A simpler diagnostic method to assess hirsutism in the Iranian population: based on modified Ferriman-Gallwey scoring system (Tehran Lipid and Glucose Study). Iranian Journal of Endocrinology and Metabolism, 15 (3). pp. 303-310.

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Abstract

Introduction: Hirsutism is a common endocrine disorder among reproductive women. There is no clear definition and criterion for the clinical evaluation and diagnosis of hirsutism. The aim of present study is to introduce a simpler diagnostic method on the basis of modified Ferriman-Gallwey (mF-G) system, which examines fewer body areas, but with the same sensitivity, specificity and positive predictive value (PPV).

Materials and Methods: A one thousand women, aged 18-45 years, participants of the Tehran Lipid and Glucose Study, were recruited by random systematic sampling. Data were collected by a questionnaire and clinical examination. The total mF-G score was calculated and ROC curve was drawn for subsets of areas. The new cut-off points were calculated for those subsets with optimal sensitivity, specificity, positive and negative predictive value and concordance percentage.

Results: The subset of 5 areas of the lips, chin, thighs, upper and lower abdomen (cut-off point 5), had sensitivity and specificity of 97/5% and 89/9% (R²= 0/92%, P<0.0001) respectively, and was the nearest subset to mF-G method. The subset of lip, abdomen and thighs (cut- off point 4) was 91/5% sensitive and 92% specific, with the highest PPV (72/2%) and concordance percentage (91/9%) with the golden standard (mF-G score ≥ 8).

Conclusion: Using the 3 area subset of lip+ lower abdomen+ thighs serves as a simple and more accepted method for hirsutism assessment and can be used in wide epidemiologic studies.

Item ID:	77740
Item Type:	Article (Research - C1)
ISSN:	1683-5476
Date Deposited:	01 Jan 2025 23:52
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320208 Endocrinology @ 50% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3215 Reproductive medicine > 321502 Obstetrics and gynaecology @ 50%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 100%
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