Root Canal Microbiome Associated with Asymptomatic Apical Periodontitis

Rodrigues Amaral, Rodrigo, Braga, Tiago, Siqueira, Jose F., Rocas, Isabela N., Coelho da Costa Rachid, Caio Tavora, Guimarães Oliveira, Anna Gabriella, Ilma de Souza Cortes, Maria, and Love, Robert Mathew (2022) Root Canal Microbiome Associated with Asymptomatic Apical Periodontitis. In: [Presented at the ANZ IADR 61st Scientific Meeting]. 993798902. From: ANZ IADR 61st Scientific Meeting, 26-28 September 2022, Melbourne, VIC, Australia.

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Root canal samples from 25 patients (ethics committee approval CAAE 9713 1918 7 0000 5137 )were prepared for DNA sequencing analysis Inclusion criteria were patients presenting no systemic disease, teeth with a single root and a single canal presenting with a carious lesion with intact pulp chamber walls, pulp necrosis confirmed by pulp sensibility tests, and clinical and radiographic evidence of asymptomatic primary apical periodontitis with no sinus tract.

Bacterial diversity of the microbiome was identified and compared between cases and to the size of related periapical lesions Statistical analysis of the operational taxonomic unit distribution ( was performed using PCoA with Bray Curtis distance and PCoA Two Way Permanova Fisher Exact test was used to evaluate the prevalence of different OTUs related to small and large periapical lesions.

Item ID: 76921
Item Type: Conference Item (Poster)
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Date Deposited: 30 Nov 2022 23:47
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3203 Dentistry > 320304 Endodontics @ 50%
31 BIOLOGICAL SCIENCES > 3107 Microbiology > 310701 Bacteriology @ 50%
SEO Codes: 20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 50%
20 HEALTH > 2099 Other health > 209999 Other health not elsewhere classified @ 50%
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