Case of the disappearing drusen
Haider, Ali S., Wight, Joel, and Reddie, Ian C. (2023) Case of the disappearing drusen. Canadian Journal of Ophthalmology, 58 (2). e71-e72.
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Abstract
A 66-year-old man with age-related macular degeneration was admitted for new left cerebellar and right parietal hemorrhagic tumours. Excisional biopsy of the left cerebellar lesion demonstrated primary CNS lymphoma (PCNSL) of diffuse large B-cell morphology.
No intraocular inflammation was present. Fundus examination revealed numerous drusen at the posterior pole of the left eye only, confirmed as sub–retinal pigment epithelium (sub-RPE) deposits on optical coherence tomography. Complete resolution of these unilateral sub-RPE drusenoid deposits occurred with systemic treatment for PCNSL alone using methotrexate, cytarabine, thioepta, and rituximab (MATRix) chemotherapy. No diagnostic vitrectomy was needed.
In this photo essay we illustrate the spontaneous resolution of sub-RPE drusenoid deposits with systemic chemotherapy.
| Item ID: | 76569 |
|---|---|
| Item Type: | Article (Case Study) |
| ISSN: | 1715-3360 |
| Copyright Information: | © 2022 Published by Elsevier Inc. on behalf of Canadian Ophthalmological Society. |
| Date Deposited: | 01 Mar 2023 06:31 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3212 Ophthalmology and optometry > 321201 Ophthalmology @ 100% |
| SEO Codes: | 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100% |
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