Plasma polymers from oregano secondary metabolites: Antibacterial and biocompatible plant-based polymers

Romo-Rico, Jesus, Krishna, Smriti Murali, Golledge, Jonathan, Hayles, Andrew, Vasilev, Krasimir, and Jacob, Mohan V. (2022) Plasma polymers from oregano secondary metabolites: Antibacterial and biocompatible plant-based polymers. Plasma Processes and Polymers, 19 (7). 2100220.

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Abstract

Bacterial infection of chronic wounds is a major healthcare problem that affects the quality of life of millions of patients worldwide and leads to a substantial healthcare cost burden. This project focused on the manufacture of a potential wound healing agent. Plasma polymers from oregano secondary metabolites (PP-OSMs) were fabricated by radiofrequency plasma-enhanced chemical vapor deposition (RF-PECVD) in continuous and pulse plasma modes at room temperature. The surface, biocompatibility, and antibacterial properties of the PP-OSMs were investigated. Polymers fabricated by RF-PECVD retained the functional groups of OSMs, promoted human dermal fibroblast adhesion, inhibited Staphylococcus aureus attachment, and eliminated Pseudomonas aeruginosa. The PP-OSM coatings are potential candidates for use in medical applications where cell biocompatibility and antibacterial properties are required.

Item ID: 74720
Item Type: Article (Research - C1)
ISSN: 1612-8869
Keywords: antibacterial, biocompatible, oregano, plant secondary metabolites, plasma polymers
Copyright Information: © 2022 The Authors. Plasma Processes and Polymers published by Wiley‐VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Funders: National Health and Medical Research Council (NHMRC)
Projects and Grants: NHMRC 1194466, NHMRC 1117061
Date Deposited: 29 Nov 2022 02:22
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3206 Medical biotechnology > 320699 Medical biotechnology not elsewhere classified @ 50%
40 ENGINEERING > 4003 Biomedical engineering > 400302 Biomaterials @ 50%
SEO Codes: 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 100%
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