Seroprevalence of dengue, Zika, chikungunya and Ross River viruses across the Solomon Islands

Russell, Tanya L., Horwood, Paul F., Harrington, Humpress, Apairamo, Allan, Kama, Nathan J., Bobogare, Albino, Maclaren, David, and Burkot, Thomas R. (2022) Seroprevalence of dengue, Zika, chikungunya and Ross River viruses across the Solomon Islands. PLoS Neglected Tropical Diseases, 16 (2). e0009848.

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Abstract

Across the Pacific, and including in the Solomon Islands, outbreaks of arboviruses such as dengue, chikungunya, and Zika are increasing in frequency, scale and impact. Outbreaks of mosquito-borne disease have the potential to overwhelm the health systems of small island nations. This study mapped the seroprevalence of dengue, Zika, chikungunya and Ross River viruses in 5 study sites in the Solomon Islands. Serum samples from 1,021 participants were analysed by ELISA. Overall, 56% of participants were flavivirus-seropositive for dengue (28%), Zika (1%) or both flaviviruses (27%); and 53% of participants were alpha-virus-seropositive for chikungunya (3%), Ross River virus (31%) or both alphaviruses (18%). Seroprevalence for both flaviviruses and alphaviruses varied by village and age of the participant. The most prevalent arboviruses in the Solomon Islands were dengue and Ross River virus. The high seroprevalence of dengue suggests that herd immunity may be a driver of dengue outbreak dynamics in the Solomon Islands. Despite being undetected prior to this survey, serology results suggest that Ross River virus transmission is endemic. There is a real need to increase the diagnostic capacities for each of the arboviruses to support effective case management and to provide timely information to inform vector control efforts and other outbreak mitigation interventions.

Item ID: 74622
Item Type: Article (Research - C1)
ISSN: 1935-2735
Copyright Information: © 2022 Russell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Date Deposited: 14 Jun 2022 03:42
FoR Codes: 42 HEALTH SCIENCES > 4202 Epidemiology > 420207 Major global burdens of disease @ 50%
42 HEALTH SCIENCES > 4203 Health services and systems > 420310 Health surveillance @ 50%
SEO Codes: 20 HEALTH > 2004 Public health (excl. specific population health) > 200404 Disease distribution and transmission (incl. surveillance and response) @ 100%
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