Khan, Munad, Nesbitt, Alexander L., Loganathan, Ajanthan, Antoniou, Stefan, Evans, Garrath, Smith, Philip, and Pridgeon, Simon W. (2021) Comparing outcomes of transurethral resection of the prostate in men with greater than or less than 100 cc prostate volume: a single-centre study. Journal of Urological Surgery, 8 (2). pp. 92-97.

PDF (Published Version) - Published Version Restricted to Repository staff only

 

2

2

Abstract

Objective: This study describes the pen-operative results, safety, and functional outcomes of transurethral resection of the prostate (TURP) performed in men with benign prostatic hyperplasia [or hypertrophy; (BPH)] and a prostate gland volume >= 100 cc.

Materials and Methods: A retrospective analysis of a cohort of patients undergoing TURP at a single institution over four years was undertaken. Patients with known prostate cancer were excluded. Clinical outcomes were between men with a prostate volume of >= 100 cc and men with a prostate volume <100 cc. Functional outcomes were assessed by defining a series of measurable post-operative lower urinary tract symptoms (LOTS) events" and comparing the time-to-event profile using a Kaplan-Meier estimator.

Results: Out of a total of 238 men who underwent TURP for BPH during the study period, 72 had a prostate volume >= 100 cc (30%). Baseline demographics were similar to the group of patients with a prostate volume <100 cc. Patients with large prostates had a significantly longer mean operating time (56 vs 98 minutes, p<0.0001). The pen-operative complication profile and post-operative complication rate were similar between the two groups. During a median follow-up period of 27 months (range, 2-54 months), no difference in LUTS events-free survival was observed (p=0.93).

Conclusion: Our results show that TURP can be safely performed in patients with large prostate glands (>= 100 cc). Although operating times were longer in the large prostate group, this did not significantly affect the complication rate nor compromise a good functional outcome.

Actions (Repository Staff Only)

Item Control Page