Effect of short-term dietary exposure on metal assimilation and metallothionein induction in the estuarine fish Pseudogobius sp.

McDonald, Sarah, Hassell, Kathryn, and Cresswell, Tom (2021) Effect of short-term dietary exposure on metal assimilation and metallothionein induction in the estuarine fish Pseudogobius sp. Science of the Total Environment, 772. 145042.

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Abstract

Metals introduced into the urban aquatic environment through anthropogenic activities have the potential to accumulate in organisms via multiple uptake routes. Understanding the impact different routes have on metal accumulation is important for the continued management of these ecosystems, where current water quality guidelines (WQGs) tend to be derived from aqueous metal exposure tests. In this study, the estuarine fish Pseudogobius sp. was exposed to a mixture of cadmium (Cd) and zinc (Zn) radiotracers dissolved in water or present in experimental food. Metal-spiked food was presented to fish as a single ‘pulse-chase’ feed or as three consecutive feeds, where the cumulative metal dose provided by both treatments was equal. Fish did not accumulate either metal from water, even after the length of exposure was increased from 12 h to 36 h. Fish did accumulate metals from diet and the assimilation efficiency (AE) was low following a single feed (12% for both Cd and Zn). Following multiple feeds fish displayed a significantly higher AE for zinc only, suggesting that fish are susceptible to retention of dietary Zn over an extended time period albeit at lower daily loadings. The final body burden and efflux rate did not differ between feeding regimes. Tissue accumulation of Cd and Zn indicated metal specific distribution. The gastro-intestinal (GI) tract contained >90% of total Cd body burden, whilst the carcass accounted for the majority (70–88%) of Zn body burden. There was significant induction of the biomarker metallothionein (MT) in the GI tract. These results demonstrate the differences in Cd and Zn metal uptake characteristics in this estuarine fish species, and how feeding frequency and metal loading of food may influence assimilation. This study highlights the importance of considering the inclusion of dietary exposures in WQG frameworks.

Item ID: 71557
Item Type: Article (Research - C1)
ISSN: 1879-1026
Keywords: Biodistribution, Biomarker, Cadmium, Food, Radiotracer, Water, Zinc
Copyright Information: © 2021 Elsevier B.V. All rights reserved.
Date Deposited: 07 Feb 2022 23:58
FoR Codes: 41 ENVIRONMENTAL SCIENCES > 4102 Ecological applications > 410201 Bioavailability and ecotoxicology @ 50%
31 BIOLOGICAL SCIENCES > 3103 Ecology > 310304 Freshwater ecology @ 50%
SEO Codes: 18 ENVIRONMENTAL MANAGEMENT > 1803 Fresh, ground and surface water systems and management > 180306 Measurement and assessment of freshwater quality (incl. physical and chemical conditions of water) @ 100%
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