Health challenges and comorbidities experienced by people living with Human Immunodeficiency Virus in developed nations: a systematic review

Johnson, Lisa, and Flavell, Carol Ann (2021) Health challenges and comorbidities experienced by people living with Human Immunodeficiency Virus in developed nations: a systematic review. HIV Nursing, 21 (2). pp. 29-53.

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Abstract

Introduction: Studies have reported the prevalence, incidence and risk of health challenges and comorbidities experienced by people living with HIV (PLHIV) in developed countries. Yet, no systematic review to appraise and summate these studies exists.

Methods: Electronic database searches included studies conducted in developed countries which reported health challenges and comorbidities in PLHIV compared to a HIV negative population. Critical appraisal was conducted using the Appraisal Tool for Cross Sectional Studies (AXIS).

Results: Eligible studies (n = 51) were of moderate to high methodological quality (range: 7-19/20). PLHIV had increased rates or risk of ischaemic stroke, myocardial infarction, reduced bone mineral density, lung and anal cancer, chronic obstructive pulmonary disease, lung infections, and peripheral lipodystrophy.

Conclusions: In developed countries several health challenges and comorbidities remain of greater concern in PLHIV compared to HIV negative individuals. Evidence for other comorbidities remains limited or inconclusive, and requires further research.

Item ID: 70799
Item Type: Article (Research - C1)
ISSN: 1474-7359
Keywords: Adult, AIDS, Developed Countries, HIV, Health, Review
Copyright Information: All papers in the journal are licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, even commercially as long as the original work is properly cited.
Date Deposited: 31 Jan 2022 23:08
FoR Codes: 42 HEALTH SCIENCES > 4201 Allied health and rehabilitation science > 420106 Physiotherapy @ 100%
SEO Codes: 20 HEALTH > 2004 Public health (excl. specific population health) > 200407 Health status (incl. wellbeing) @ 100%
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