Wongtongkam, Nualnong (2022) Impact of comorbid substance use and infectious and non-communicable diseases in a cross-sectional study, Thailand. Journal of Substance Use, 27 (5). pp. 543-549.

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Abstract

Background: Substance use has been recognized as increasing risk for concomitant infectious and non-communicable diseases (NCDs), which has contributed to poor treatment outcomes and a social burden, particularly in low-middle income countries. This study aimed at investigating effects of comorbid substance use and infectious and NCDs on psychological, suicidal behaviors and cognitive assessments.

Methods: In a cross-sectional study, 141 participants were recruited from six wards in one rehabilitation center and data consisting of demographic and personal characteristics and three self-administered instruments were obtained. Descriptive statistics, Mann–Whitney U test and binary logistic regression were used for data analysis.

Results: Findings showed that participants’ age and reasons for hospitalization were significantly related to comorbid substance use, χ2(48) = 97.348, p < .05, and χ2(60) = 84.790, p < .05, respectively. Compared with methamphetamine dependence, participants with concomitant methamphetamine psychosis were five times more likely to develop severe anxiety disorders (OR = 5.00, 95% CI = 1.16–21.45) but there were no significant differences for suicidal behaviors and cognitive impairment.

Conclusions: Because of severe anxiety symptoms, treatment for users with comorbid methamphetamine and psychosis should be closely monitored to increase therapeutic effects.

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