SARS CoV-2 aerosol: How far it can travel to the lower airways?

Islam, Mohammad S., Larpruenrudee, Puchanee, Paul, Akshoy Ranjan, Paul, Gunther, Gemci, Tevfik, Gu, Yuantong, and Saha, Suvash C. (2021) SARS CoV-2 aerosol: How far it can travel to the lower airways? Physics of Fluids, 33 (6). 061903.

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Abstract

The recent outbreak of the SARS CoV-2 virus has had a significant effect on human respiratory health around the world. The contagious disease infected a large proportion of the world population, resulting in long-term health issues and an excessive mortality rate. The SARS CoV-2 virus can spread as small aerosols and enters the respiratory systems through the oral (nose or mouth) airway. The SARS CoV-2 particle transport to the mouth-throat and upper airways is analyzed by the available literature. Due to the tiny size, the virus can travel to the terminal airways of the respiratory system and form a severe health hazard. There is a gap in the understanding of the SARS CoV-2 particle transport to the terminal airways. The present study investigated the SARS CoV-2 virus particle transport and deposition to the terminal airways in a complex 17-generation lung model. This first-ever study demonstrates how far SARS CoV-2 particles can travel in the respiratory system. ANSYS Fluent solver was used to simulate the virus particle transport during sleep and light and heavy activity conditions. Numerical results demonstrate that a higher percentage of the virus particles are trapped at the upper airways when sleeping and in a light activity condition. More virus particles have lung contact in the right lung than the left lung. A comprehensive lobe specific deposition and deposition concentration study was performed. The results of this study provide a precise knowledge of the SARs CoV-2 particle transport to the lower branches and could help the lung health risk assessment system.

Item ID: 70347
Item Type: Article (Research - C1)
ISSN: 1089-7666
Copyright Information: © 2021 Author(s).
Funders: Australian Research Council (ARC)
Projects and Grants: ARC Grant No. DP180103009, ARC Grant No. IC190100020
Date Deposited: 05 Apr 2022 04:49
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