Early-onset SARS-CoV-2 infection in neonates born to COVID positive mothers

Rao, Varsha, and Hariharan, Gopakumar (2021) Early-onset SARS-CoV-2 infection in neonates born to COVID positive mothers. Acta Paediatrica, 110 (8). pp. 2480-2481.

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[Extract] The global pandemic caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) has affected a substantial number of pregnant women.1 Although neonates have been reported to be positive for the virus infection, there is paucity of data on outcome and mode of transmission.

The predominant mode of transmission of SARS-CoV-2 is aerosol or direct contact.2, 3 Evidence suggests that respiratory viruses are not commonly transmitted in-utero. Although vertical transmission has been postulated as a mode of transmission in early-onset SARS-CoV-2 infection in neonates, there is no conclusive evidence to support this due to limitations related to sensitivity and specificity of diagnostic testing, variation in timing of tests for the virus and appropriate sample to determine infection conclusively.4 Furthermore, there is lack of consensus regarding definition of vertical transmission.

Item ID: 70242
Item Type: Article (Commentary)
ISSN: 1651-2227
Copyright Information: ©2021 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd.
Date Deposited: 29 Jun 2022 23:58
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320211 Infectious diseases @ 50%
32 BIOMEDICAL AND CLINICAL SCIENCES > 3213 Paediatrics > 321303 Neonatology @ 50%
SEO Codes: 20 HEALTH > 2005 Specific population health (excl. Indigenous health) > 200506 Neonatal and child health @ 100%
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