The lower limit of quantification in pharmacokinetic analyses
Woodward, Andrew, and Whittem, Ted (2019) The lower limit of quantification in pharmacokinetic analyses. Journal of Veterinary Pharmacology and Therapeutics, 42 (6). pp. 585-587.
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DOI: 10.1111/jvp.12778
View at Publisher Website: https://doi.org/10.1111/jvp.12778
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Abstract
Pharmacokinetic (PK) analyses rely fundamentally on independent measurements of drug concentrations in biological matrices, traditionally using chromatographic analytical methods. These methods have imperfect performance and introduce measurement error to the experiment. Commonly, the measurement error is used to constrain the report of analytical outputs. An important issue in PK is the influence of these analytical constraints on available inferences.
| Item ID: | 69750 |
|---|---|
| Item Type: | Article (Commentary) |
| ISSN: | 1365-2885 |
| Copyright Information: | © 2019 John Wiley & Sons Ltd |
| Date Deposited: | 02 Aug 2022 23:00 |
| FoR Codes: | 30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300911 Veterinary pharmacology @ 100% |
| SEO Codes: | 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280112 Expanding knowledge in the health sciences @ 100% |
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