Echocardiographic screening detects a significant burden of Rheumatic Heart Disease in Australian Torres Strait Islander children and missed opportunities for its prevention

Hempenstall, Allison, Howell, Erin, Kang, Katherine, Chau, Ken W.T., Browne, Amylou, Kris, Ella, Wapau, Hylda, Pilot, Pelista, Smith, Simon, Reeves, Benjamin, and Hanson, Joshua (2021) Echocardiographic screening detects a significant burden of Rheumatic Heart Disease in Australian Torres Strait Islander children and missed opportunities for its prevention. American Journal of Tropical Medicine and Hygiene, 104 (4). pp. 1211-1214.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only until 7 April 2022.

View at Publisher Website: https://doi.org/10.4269/ajtmh.20-0846
 
3


Abstract

Rheumatic heart disease (RHD) is almost entirely preventable, but its incidence in indigenous Australians remains one of the highest in the world. A community-based echocardiogram screening program of 862 Torres Strait Islander children identified 25 (2.9%) new cases of RHD. Among these 25 children, 5/7 (71%) prior acute rheumatic fever presentations had not been recognized. There was a history of microbiologically confirmed group A Streptococcus infection in 17/25 (68%) children with RHD compared with 9/25 (36%) controls (odds ratio [OR] [95% CI]: 3.78 [1.17–12.19], P = 0.03). This was more likely to be a skin swab (16/25 [64%] cases versus 6/25 [24%] controls) than a throat swab (1/25 [4%] cases versus 3/25 [12%] controls) (OR [95% CI]: 5.33 [1.51–18.90] [P = 0.01]), supporting a role for skin infection in RHD pathogenesis. Household crowding and unemployment were common in the cohort, emphasizing the need for prioritizing strategies that address the social determinants of health.

Item ID: 67570
Item Type: Article (Research - C1)
ISSN: 1476-1645
Keywords: Rheumatic Fever; Benzathine Penicillin; Chorea
Copyright Information: © Copyright 2021 Elsevier B.V., All rights reserved.
Date Deposited: 29 Jul 2021 04:49
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3201 Cardiovascular medicine and haematology > 320101 Cardiology (incl. cardiovascular diseases) @ 100%
SEO Codes: 20 HEALTH > 2002 Evaluation of health and support services > 200201 Determinants of health @ 100%
Downloads: Total: 3
Last 12 Months: 3
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page