Impact of community treatment with ivermectin for the control of scabies on the prevalence of antibodies to Strongyloides stercoralis in children

Marks, Michael, Gwyn, Sarah, Toloka, Hilary, Kositz, Christian, Asugeni, James, Asugeni, Rowena, Diau, Jason, Kaldor, John M., Romani, Lucia, Redman-Maclaren, Michelle, MacLaren, David, Solomon, Anthony W., Mabey, David C.W., Steer, Andrew C., and Martin, Diana (2020) Impact of community treatment with ivermectin for the control of scabies on the prevalence of antibodies to Strongyloides stercoralis in children. Clinical Infectious Diseases, 71 (12). pp. 3226-3228.

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Abstract

The prevalence of antibodies to Strongyloides stercoralis was measured in 0-12-year-olds using a bead-based immunoassay before and after ivermectin mass drug administration (MDA) for scabies in the Solomon Islands. Seroprevalence was 9.3% before and 5.1% after MDA (P†=†.019), demonstrating collateral benefits of ivermectin MDA in this setting.

Item ID: 66585
Item Type: Article (Research - C1)
ISSN: 1537-6591
Keywords: ivermectin, neglected tropical diseases, scabies, Strongyloides
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Copyright Information: © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Sensitivity Note: Data collected in Solomon Islands
Funders: Wellcome Trust (WT)
Projects and Grants: WT Clinical PhD Fellowship (grant number 102807)
Date Deposited: 03 Mar 2021 01:30
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320704 Medical parasitology @ 100%
SEO Codes: 20 HEALTH > 2004 Public health (excl. specific population health) > 200404 Disease distribution and transmission (incl. surveillance and response) @ 100%
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