Oliva, Jessica L., Leung, Sumie, Croft, Rodney J., O'Neill, Barry V., Stout, Julie C., and Nathan, Pradeep J. (2011) Evidence for sex differences in the loudness dependence of the auditory evoked potential in humans. Human Psychopharmacology: Clinical and Experimental, 26 (2). pp. 172-176.

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Abstract

Objective: The loudness dependence of the auditory evoked potential (LDAEP) has been suggested as a marker of the serotonin system, although studies directly examining the relationship between acute changes in serotonin and the LDAEP have been inconsistent. Given the reported sex dichotomy in serotonin neurotransmission, this study examined if there are sex differences in the LDAEP.

Methods: Data from 65 healthy participants from four independent studies were pooled, and their N1/P2 slopes were quantified.

Results: Mean N1/P2 slopes for female participants were higher than those for male participants (p < 0.0001).

Conclusion: These findings suggest that the LDAEP is modulated by sex potentially because of differences in serotonergic neurotransmission, and these differences may account for some of the inconsistent findings linking serotonin function and LDAEP.

Item ID:	65914
Item Type:	Article (Research - C1)
ISSN:	1099-1077
Keywords:	sex; gender; loudness dependence; auditory evoked potential; LDAEP; serotonin
Copyright Information:	Copyright © 2011 John Wiley & Sons, Ltd.
Date Deposited:	03 Feb 2021 01:41
FoR Codes:	17 PSYCHOLOGY AND COGNITIVE SCIENCES > 1701 Psychology > 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) @ 50% 17 PSYCHOLOGY AND COGNITIVE SCIENCES > 1702 Cognitive Science > 170205 Neurocognitive Patterns and Neural Networks @ 50%
SEO Codes:	97 EXPANDING KNOWLEDGE > 970117 Expanding Knowledge in Psychology and Cognitive Sciences @ 100%
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