Childhood health and developmental outcomes after cesarean birth in an Australian cohort

Robson, Stephen J., Vally, Hassan, Abdel-Latif, Mohamed E., Yu, Maggie, and Westrupp, Elizabeth (2015) Childhood health and developmental outcomes after cesarean birth in an Australian cohort. Pediatrics, 136 (5). e1285-e1293.

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Abstract

BACKGROUND AND OBJECTIVES: Concerns have been raised about associations between cesarean delivery and childhood obesity and asthma. However, published studies have not examined the long-term neurodevelopmental outcomes or fully addressed confounding influences. We used data from the LSAC (Longitudinal Study of Australian Children) to explore the relationship between cesarean delivery and physical and socio-emotional outcomes from 0 to 7 years, taking into account confounding factors.

METHODS: Data were from 5 waves of LSAC representing 5107 children born in 2003 and 2004. Outcome measures included: global health, asthma, BMI, use of prescribed medication, general development, medical conditions and/or disabilities, special health care needs, and socio-emotional development. Models adjusted for birth factors, social vulnerability, maternal BMI, and breastfeeding.

RESULTS: Children born by cesarean delivery were more likely to have a medical condition at 2 to 3 years (odds ratio: 1.33; P = .03), use prescribed medication at 6 to 7 years (odds ratio: 1.26; P = .04), and have a higher BMI at 8 to 9 years (coefficient: 0.08; P = .05), although this last effect was mediated by maternal obesity. Parent-reported quality of life for children born by cesarean delivery was lower at 8 to 9 years (coefficient: –0.08; P = .03) but not at younger ages. Contrasting this finding, cesarean delivery was associated with better parent-reported global health at 2 to 3 years (odds ratio: 1.23; P = .05) and prosocial skills at age 6 to 7 years (coefficient: 0.09; P = .02).

CONCLUSIONS: Cesarean delivery was associated with a mix of positive and negative outcomes across early childhood, but overall there were few associations, and these were not consistent across the 5 waves. This study does not support a strong association between cesarean delivery and poorer health or neurodevelopmental outcomes in childhood.

Item ID: 65228
Item Type: Article (Research - C1)
ISSN: 1098-4275
Copyright Information: Copyright © 2015 by the American Academy of Pediatrics.
Funders: BUPA Health Foundation, National Health and Medical Research Council (NHMRC), Centre of Research Excellence in Child Language (CRECL)
Projects and Grants: NHMRC/CRECL #1023493
Date Deposited: 01 Dec 2020 05:25
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111402 Obstetrics and Gynaecology @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111403 Paediatrics @ 50%
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