Continuous flow photochemical production of antimalarials

Malakar, Padmakana (2019) Continuous flow photochemical production of antimalarials. PhD thesis, James Cook University.

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View at Publisher Website: https://doi.org/10.25903/gneg-6g72
 
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Abstract

Padmakana Malakar investigated the synthesis of antimalarial compounds using light and continuous flow operation. She developed an efficient process for the synthesis of the important antimalarial artemisinin. She likewise generated a library of novel trioxane compounds with potential antimalarial activities. She also utilized metal-organic-frameworks as advanced sensitizers for the photooxygenation to the bioactive ascaridole.

Item ID: 64922
Item Type: Thesis (PhD)
Keywords: photochemistry; photooxygenations; flow photochemistry; solar chemistry; antimalarials; artemisinin; trioxane compounds
Copyright Information: Copyright © 2019 Padmakana Malakar.
Date Deposited: 02 Nov 2020 05:01
FoR Codes: 03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030503 Organic Chemical Synthesis @ 50%
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030505 Physical Organic Chemistry @ 20%
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030504 Organic Green Chemistry @ 30%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
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