Clinical management of seafood allergy

Davis, Carla M., Gupta, Ruchi S., Aktas, Ozge N., Diaz, Veronica, Kamath, Sandip D., and Lopata, Andreas L. (2020) Clinical management of seafood allergy. Journal Of Allergy And Clinical Immunology: In Practice, 8 (1). pp. 37-44.

PDF (Published Version) - Published Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (485kB) | Preview
View at Publisher Website:


Seafood plays an important role in human nutrition and health. A good patient workup and sensitive diagnostic analysis of IgE antibody reactivity can distinguish between a true seafood allergy and other adverse reactions generated by toxins or parasites contaminating ingested seafood. The 2 most important seafood groupings include the fish and shellfish. Shellfish, in the context of seafood consumption, constitutes a diverse group of species subdivided into crustaceans and mollusks. The prevalence of shellfish allergy seems to be higher than that of fish allergy, with an estimate of up to 3% in the adult population and fin fish allergy prevalence of approximately 1%. Clinical evaluation of the seafood-allergic patient involves obtaining a detailed history and obtaining in vivo and/or in vitro testing with careful interpretation of results with consideration of cross-reactivity features of the major allergens. Oral food challenge is useful not only for the diagnosis but also for avoiding unnecessary dietary restrictions. In this review, we highlight some of the recent reports to provide solid clinical and laboratory tools for the differentiation of fish allergy from shellfish allergy, enabling best treatment and management of these patients.

Item ID: 63529
Item Type: Article (Research - C1)
ISSN: 2213-2201
Keywords: Fish allergy; Shellfish allergy; Crustacean; Mollusk; Diagnosis of fish allergy; Skin prick test; Oral food challenge
Copyright Information: © 2019 The Authors. Published by Elsevier Inc. on behalf of the American Academyof Allergy, Asthma & Immunology. This is an open access article under the CCBY-NC-ND license (
Date Deposited: 23 Jun 2020 02:32
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320401 Allergy @ 90%
32 BIOMEDICAL AND CLINICAL SCIENCES > 3206 Medical biotechnology > 320602 Medical biotechnology diagnostics (incl. biosensors) @ 10%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 60%
92 HEALTH > 9202 Health and Support Services > 920203 Diagnostic Methods @ 40%
Downloads: Total: 855
Last 12 Months: 163
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page