Consuming a small-moderate dose of red wine alone can alter the glucose-insulin relationship

Kokavec, Anna, and Halloran, Mark A. (2010) Consuming a small-moderate dose of red wine alone can alter the glucose-insulin relationship. Canadian Journal of Physiology and Pharmacology, 88 (12). pp. 1147-1156.

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The aim in the present study was to assess the effect of small-moderate red wine ingestion on serum insulin and plasma glucose concentration when nutritional status is varied. Twenty non-diabetic males (19-22 years) participated in the study. In the fasting trial all participants underwent a six hour fast prior to consuming 4 standard units of red wine (40g alcohol) or the equivalent amount of placebo as dealcoholised wine (containing < .5% alcohol, 0% resveratrol) over a 135-min period. Alternatively, in the feeding trial participants consumed food for 45-min prior to ingesting 4 standard units of red wine (40g alcohol) or placebo for 135-min. Serum insulin and plasma glucose was assessed at regular 45-min intervals during both trials. The results showed a significant decrease in the level of serum insulin and no significant change in plasma glucose concentration in the fasting trial. Alternatively, a significant alcohol-induced decrease in plasma glucose and no change in serum insulin occurred when red wine is consumed alone after food. It was concluded that red wine can alter the glucose-insulin relationship and ingesting red wine alone without food should not be encouraged in non-diabetic individuals.

Item ID: 63461
Item Type: Article (Research - C1)
ISSN: 1205-7541
Keywords: alcohol, insulin, feeding, wine, glucose, fasting
Date Deposited: 05 Aug 2021 05:45
FoR Codes: 17 PSYCHOLOGY AND COGNITIVE SCIENCES > 1701 Psychology > 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) @ 100%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920401 Behaviour and Health @ 100%
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