A practical guide to the stereological assessment of glomerular number, size, and cellular composition

Sutherland, Megan R., Vojisavljevic, Danica, and Black, Mary Jane (2020) A practical guide to the stereological assessment of glomerular number, size, and cellular composition. The Anatomical Record, 303 (10). pp. 2679-2692.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1002/ar.24361
 
2


Abstract

The evaluation of a range of measures in the kidneys, such as developmental stage, rate and success, injury, and disease processes, relies on obtaining information on the three-dimensional structure of the renal corpuscles, and in particular the glomerular capillary tufts. To do this in the most accurate, comprehensive, and unbiased manner depends on a knowledge of stereological methods. In this article, we provide a practical guide for researchers on how to quantitate a number of structures in the kidneys, including the estimation of total glomerular number, glomerular capillary length and filtration surface area, and the cellular composition of individual glomeruli. Guidance is also provided on how to apply these methods to kidneys at different sizes and levels of maturity.

Item ID: 62208
Item Type: Article (Research - C1)
ISSN: 1932-8494
Keywords: glomerulus, kidney development, nephron nubmber, podocyte, stereology.
Copyright Information: © 2020 American Association for Anatomy
Date Deposited: 09 Dec 2020 03:41
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
Downloads: Total: 2
Last 12 Months: 1
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page