Buprenorphine analgesia: new adverse effects emerge

Letson, Hayley L., and Dobson, Geoffrey P. (2020) Buprenorphine analgesia: new adverse effects emerge. Shock. (In Press)

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Abstract

[Excerpt] To the Editor: We read with interest the Rapid Communication of Chen et al. who found repetitive administration of the opioid analgesic buprenorphine in a mouse model of cecal ligation and puncture (CLP) markedly elevated sepsis surrogate markers(interleukin-6, KC, monocyte chemoattractant protein-1, andgranulocyte-colony stimulating factor) in 20% to 60% of septicanimals (1).

Item ID: 62089
Item Type: Article (Commentary)
ISSN: 1540-0514
Funders: USSOCOM
Projects and Grants: W81XWH-USSOCOM-BAA-15-1
Date Deposited: 30 Mar 2020 23:21
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1116 Medical Physiology > 111699 Medical Physiology not elsewhere classified @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920199 Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified @ 100%
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