Low proportions of folic acid deficiency after introduction of mandatory folic acid fortification in remote areas of northern Queensland, Australia: a secondary health data analysis

Slagman, Anna, Harriss, Linton, Campbell, Sandra, Muller, Reinhold, and McDermott, Robyn (2019) Low proportions of folic acid deficiency after introduction of mandatory folic acid fortification in remote areas of northern Queensland, Australia: a secondary health data analysis. Biomarkers, 24 (7). pp. 684-691.

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Abstract

Background: Australia implemented mandatory folic acid fortification of bread-making flour in 2009.

Objective: To assess the impact of folic acid fortification in remote vs. regional urban areas and Indigenous vs. non-Indigenous populations in northern Queensland.

Methods: Routinely collected data on folic acid measurements in remote areas and two regional urban centres in northern Queensland between 2004 and 2015 were analysed (n = 13,929) dichotomously (folic deficient vs. non-deficient).

Results: Overall prevalence of folic acid deficiency was 3.2% (235/7282) in urban centres compared with 7.2% (480/6647) in remote areas (p < 0.001), and 9.3% (393/4240) in the Indigenous population compared with 3.2% (273/8451) in the non-Indigenous population (p < 0.001). Prevalence of folic acid deficiency dropped from 12.2% (n = 481) in 2004-2008 to 1.5% (n = 126) in 2010-2015 (p < 0.001). This translates into a relative risk reduction (RRR) of 88%. RRR was 79% (7.2% vs. 1.5%) in urban centres, 91% (17.3% vs. 1.5%) in remote areas, 92% (20.5% vs. 1.6%) in the Indigenous population and 80% (7.4% vs. 1.5%) in the non-Indigenous population (p < 0.001 for all).

Conclusions: Substantial declines of folic acid deficiency to low and comparable proportions in former high-risk populations indicate that mandatory folic acid fortification of flour has had a population-wide benefit in northern Queensland.

Item ID: 60406
Item Type: Article (Research - C1)
ISSN: 1366-5804
Keywords: folic acid, indigenous, nutrition, red cell folate, secondary health data, remote
Copyright Information: (C) 2019 Informa UK Limited, trading as Taylor & Francis Group
Funders: Queensland Health (QH)
Projects and Grants: QH SCRF-Round 3
Date Deposited: 18 Sep 2019 07:35
FoR Codes: 45 INDIGENOUS STUDIES > 4504 Aboriginal and Torres Strait Islander health and wellbeing > 450405 Aboriginal and Torres Strait Islander diet and nutrition @ 30%
32 BIOMEDICAL AND CLINICAL SCIENCES > 3210 Nutrition and dietetics > 321005 Public health nutrition @ 70%
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